When I was undergrad, one of my very dear friends had a sibling with GID. This is not funny, it is a legitimate and frustrating condition and to anyone out there who has it or loves someone who has it, I'm very sorry and hang in there.
That being said, there will be a laugh coming I promise.
This sibling started his transition from female to male during our first year of college. So, while many of us had met our friend's sister, we also had seen her family on many occasions after the transition process had been started. Well, most of us had.
Late in our senior year, my friend's family came to visit on an emergency visit (this is also very, very not funny...hang in there). She had been in the hospital for a few days and had just returned home. Needless to say friends stopped by to visit her.
While I was sitting with her and one of our other chums, S, her sibling, who was now very obviously identifiable as her brother, walked through to go to the kitchen. Cue S:
"I didn't know you had a brother, just a sister. Where is your sister anyway? I haven't seen her in a while."
By this point I have noticed that the room we are in is VERY open to the kitchen and I have started staring directly at S with my best "shut the fuck up you moron" look. But she did not stop.
"No really what happened to your sister? Don't you get along? Why have you never introduced your brother."
More glaring on my part
"It's not very nice of your sister not to come visit" and on, and on for what must have been about five minutes, by the end of which I thought my eyes were going to pop out of my head or I was going to strangle this girl (which would have been kinda funny, but not the point).
Eventually she stopped and the whole thing was just let go. My friend's brother was very understanding about the whole thing and all turned out okay.
But, friends, do you know what S was studying in school and later went on to pursue as a career?...
That girl is literally a rocket scientist.
...we are all so fucked.